MSD-D
MSD-D is a potent and frequency-dependent Kv1.5 channel inhibitor with an IC50 value of 0.5 μM. MSD-D is promising for research of atrial-selective class III antiarrhythmics[2].
Product Specifications
CAS Number
182504-18-3
UNSPSC
12352005
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/msd-d.html
Smiles
N#CC1=C(C)C(SC2=CC=C(C)C=C2)=NN(C3=CC=C(OC)C=C3)C1=O
Molecular Formula
C20H17N3O2S
Molecular Weight
363.43
References & Citations
[1]Strutz-Seebohm N, et al. Comparison of potent Kv1.5 potassium channel inhibitors reveals the molecular basis for blocking kinetics and binding mode. Cell Physiol Biochem. 2007;20 (6) :791-800.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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