Chlorahololide D
Chlorahololide D is a lindane-type sesquiterpene dimer and selective potassium channel blocker. It induces G2/M cell cycle arrest and apoptosis in MCF-7 breast cancer cells by elevating ROS and modulating Bcl-2/Bax/FAK pathways, demonstrating anti-proliferative, anti-migratory, and anti-angiogenic activity in vivo.
Product Specifications
CAS Number
943136-39-8
Product Name Alternative
Chlorahololide D
Field of Research
Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.43% (May vary between batches)
Smiles
C (\C (OC) =O) (/C) =C\1/[C@@]2 ([C@@]34[C@] ([C@@]5 (C) [C@]6 ([C@] (C6) ([C@] (COC (/C (=C/C) /C) =O) (O) [C@@]5 (CC3=C (COC (C) =O) C (=O) O4) [H]) [H]) [H]) (CC7=C2[C@] (C) ([C@]8 ([C@@]7 (C8) [H]) [H]) [C@@H] (O) C1=O) [H]) [H]
Molecular Formula
C38H44O11
Molecular Weight
676.75
Storage Conditions
Store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
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