Rocaglaol
Rocaglaol is a potent small molecule with anticancer activity, inducing apoptosis via the mitochondrial pathway and causing G2/M arrest through Cdc25C/Cdc2 modulation. It also exhibits neuroprotective effects in vivo by inhibiting NF-κB/AP-1 and can mitigate chemotherapy-induced cardiotoxicity. Furthermore, it and related compounds strongly inhibit protein synthesis and cell growth in vitro at low ng/mL concentrations.
Product Specifications
CAS Number
147059-46-9
Field of Research
Cell Biology
Smiles
COc1ccc (cc1) [C@@]12Oc3cc (OC) cc (OC) c3[C@]1 (O) [C@H] (O) C[C@H]2c1ccccc1
Molecular Formula
C26H26O6
Molecular Weight
434.48
Storage Conditions
-20°C
Notes
For research use only.
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