Anti-CD25 [PC-61.5.3]

Product Specifications

CAS Number

9007-83-4

Gene Name

[CD25]

NCBI Gene ID

16184

Reactivity

Mouse

Storage Conditions

Store at 4 °C for up to 3 months. For longer storage, aliquot and store at -20 °C.

Specificity

This antibody is specific for murine CD25, the 55 kDa interleukin-2 receptor alpha chain (IL-2R alpha). CD25 is expressed by early progenitors of the T and B lineage as well as by activated mature T and B lymphocytes. By itself, CD25 binds IL-2 only with low affinity. However, CD25 associates with CD122 (IL-2 receptor beta chain) and CD132 (common gamma chain) to form the high affinity IL-2 receptor. Binding of IL-2 to both the high and low affinity classes of IL-2 receptor is inhibited by the PC61.5 antibody.

Other Gene Names

[Il2ra; Il2ra; CD25; Il2r; Ly-43; Il2r; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA]

Short Name

[CD25]

Other Product Names

[Interleukin-2 receptor subunit alpha; Interleukin-2 receptor subunit alpha; interleukin-2 receptor subunit alpha; IL2-RA; IL-2-RA; p55 chain; IL-2R alpha chain; IL-2R subunit alpha; IL-2 receptor subunit alpha; interleukin 2 receptor, alpha chain; p55; CD_antigen: CD25]