Anti-TIM-2 [RMT2-14]

This antibody is specific for murine TIM-2, a transmembrane protein that is expressed on activated T cells and preferentially on differentiated Th2 cells. A blockade of TIM-2/TIM-2 ligand interaction results in T cell hyperproliferation and Th2 cytokine production. TIM-2 plays a critical role in the development of atopic disease and other Th2-biased immune responses.

[T-cell immunoglobulin and mucin domain-containing protein 2; T-cell immunoglobulin and mucin domain-containing protein 2; T-cell immunoglobulin and mucin domain-containing protein 2; T-cell immunoglobulin and mucin domain containing 2; T-cell immunoglobulin mucin receptor 2; T-cell membrane protein 2; TIMD-2; T cell immunoglobulin and mucin domain containing 2; T-cell immunoglobulin mucin receptor 2; TIM-2; T-cell membrane protein 2]