Anti-CCRL2 [BZ5B8]

Product Specifications

CAS Number

9007-83-4

Gene Name

[CCRL2]

NCBI Gene ID

54199

Reactivity

Mouse

Storage Conditions

Store at 4 °C for up to 3 months. For longer storage, aliquot and store at -20 °C.

Specificity

This antibody is specific for murine CCRL2 (formerly known as L-CCR), which is expressed on mast cells, activated macrophages, and endothelial cells. This receptor binds the leukocyte chemoattractant chemerin without triggering classical GPCR signaling, providing a specific mechanism for local enrichment of chemerin at inflammatory sites. CCRL2 presents active chemerin to leukocytes expressing the chemoattractant receptor CMKLR1/Chemr23. Chemerin can block anti-CCRL2 antibody binding.

Other Gene Names

[Ccrl2; Ccrl2; E01; Ackr5; CCR11; L-CCR; Cmkbr1l2; 1810047I05Rik; Ccr11; Lccr; L-CCR]

Short Name

[CCRL2]

Other Product Names

[C-C chemokine receptor-like 2; C-C chemokine receptor-like 2; C-C chemokine receptor-like 2; chemokine (C-C motif) receptor-like 2; Chemokine receptor CCR11; G-protein coupled beta chemokine receptor; Lipopolysaccharide-inducible C-C chemokine receptor; L-CCR]