Anti-CCRL2 [BZ5B8]
Product Specifications
CAS Number
9007-83-4
Gene Name
[CCRL2]
NCBI Gene ID
54199
Reactivity
Mouse
Storage Conditions
Store at 4 °C for up to 3 months. For longer storage, aliquot and store at -20 °C.
Specificity
This antibody is specific for murine CCRL2 (formerly known as L-CCR), which is expressed on mast cells, activated macrophages, and endothelial cells. This receptor binds the leukocyte chemoattractant chemerin without triggering classical GPCR signaling, providing a specific mechanism for local enrichment of chemerin at inflammatory sites. CCRL2 presents active chemerin to leukocytes expressing the chemoattractant receptor CMKLR1/Chemr23. Chemerin can block anti-CCRL2 antibody binding.
Other Gene Names
[Ccrl2; Ccrl2; E01; Ackr5; CCR11; L-CCR; Cmkbr1l2; 1810047I05Rik; Ccr11; Lccr; L-CCR]
Short Name
[CCRL2]
Other Product Names
[C-C chemokine receptor-like 2; C-C chemokine receptor-like 2; C-C chemokine receptor-like 2; chemokine (C-C motif) receptor-like 2; Chemokine receptor CCR11; G-protein coupled beta chemokine receptor; Lipopolysaccharide-inducible C-C chemokine receptor; L-CCR]
NCBI GI Number
698979997
NCBI Accession Number
NP_001289305.1
NCBI GB Accession Number
NM_001302376.1
Uniprot Accession Number
O35457
Available Sizes
Curated Selection
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