Anti-CD105 [MJ7/18]
Product Specifications
CAS Number
9007-83-4
Gene Name
[CD105]
NCBI Gene ID
13805
Reactivity
Mouse
Storage Conditions
Store at 4 °C for up to 3 months. For longer storage, aliquot and store at -20 °C.
Specificity
MJ7/18 binds specifically to mouse CD105. CD105 is a homodimer expressed by vascular endothelial cells. CD105 functions in adhesion and embryonic angiogenesis. CD105 is a major homodimeric glycoprotein of vascular endothelium involved in cell ahesion through integrin/RGD binding and the regulation of angiogenesis. Also acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. CD105 is also required for GDF2/BMP9 signaling through SMAD1 in endothelial cells.
Other Gene Names
[Eng; Eng; Endo; CD105; AI528660; AI662476; S-endoglin; Edg]
Short Name
[CD105]
Other Product Names
[endoglin isoform 1; Endoglin; endoglin; endoglin; Cell surface MJ7/18 antigen; CD_antigen: CD105]
NCBI GI Number
226437647
NCBI Accession Number
NP_031958.2
NCBI GB Accession Number
NP_031958.2
Uniprot Accession Number
Q63961
Available Sizes
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