Anti-CD80 [IDEC-114 (Galiximab)]
Product Specifications
CAS Number
9007-83-4
Gene Name
[CD80]
NCBI Gene ID
941
Reactivity
Human
Storage Conditions
Store at 4 °C for up to 3 months. For longer storage, aliquot and store at -20 °C.
Specificity
Galiximab is a primatized mAb which consists of human constant and primate (cynomolgus macaque) variable regions and binds specifically to CD80. CD80 is a surface glycoprotein and a member of the B7 family of costimulatory molecules. CD80 antigen regulates T cell activation (through interacting with CD28 or CD152) and is expressed transiently in antigen-presenting cells, T cells and normal B cells, and expressed consitutively on various subtypes of B-cell lymphomas.
Other Gene Names
[CD80; CD80; B7; BB1; B7-1; B7.1; LAB7; CD28LG; CD28LG1; CD28LG; CD28LG1; LAB7; B7]
Short Name
[CD80]
Other Product Names
[T-lymphocyte activation antigen CD80; T-lymphocyte activation antigen CD80; T-lymphocyte activation antigen CD80; CD80 molecule; Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1; B7; CD_antigen: CD80]
NCBI GI Number
4885123
NCBI Accession Number
NP_005182.1
NCBI GB Accession Number
NM_005191.4
Uniprot Accession Number
P33681
Available Sizes
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