Edgeworin
Edgeworin is a small molecule inhibitor of DNA polymerase beta (pol β), blocking both its lyase and polymerase activities. This inhibition of base excision repair potentiates bleomycin's cytotoxicity in vitro, making it a research tool for studying DNA repair mechanisms and combination therapies in cancer models.
Product Specifications
CAS Number
120028-43-5
Smiles
Oc1ccc2cc (Oc3ccc4ccc (=O) oc4c3) c (=O) oc2c1
Molecular Formula
C18H10O6
Molecular Weight
322.272
Storage Conditions
-20°C
Notes
For research use only.
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