HPPH
HPPH (Photochlor) is a second generation photosensitizer, which acts as a photodynamic therapy (PDT) agent.
Product Specifications
CAS Number
149402-51-7
Product Name Alternative
Photochlor
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/HPPH.html
Purity
99.92
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
OC(CC[C@H](/C1=C(C2=C3C(C)=C(N2)/C=C4C(CC)=C(C(/C=C5N/C(C(C)=C\5C(OCCCCCC)C)=C\C6=N1)=N/4)C)\CC3=O)[C@@H]6C)=O
Molecular Formula
C39H48N4O4
Molecular Weight
636.82
Precautions
H302, H315, H319, H335
References & Citations
[1]Rong P, et al. Photosensitizer loaded nano-graphene for multimodality imaging guided tumor photodynamic therapy. Theranostics. 2014 Jan 15;4 (3) :229-39.|[2]Shams M, et al. Development of photodynamic therapy regimens that control primary tumor growth and inhibit secondary disease. Cancer Immunol Immunother. 2015 Mar;64 (3) :287-97.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Frequently Asked Questions
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