HPPH

HPPH (Photochlor) is a second generation photosensitizer, which acts as a photodynamic therapy (PDT) agent.

Product Specifications

CAS Number

[149402-51-7]

Product Name Alternative

Photochlor

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/HPPH.html

Purity

99.92

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

OC(CC[C@H](/C1=C(C2=C3C(C)=C(N2)/C=C4C(CC)=C(C(/C=C5N/C(C(C)=C\5C(OCCCCCC)C)=C\C6=N1)=N/4)C)\CC3=O)[C@@H]6C)=O

Molecular Formula

C39H48N4O4

Molecular Weight

636.82

Precautions

H302, H315, H319, H335

References & Citations

[1]Rong P, et al. Photosensitizer loaded nano-graphene for multimodality imaging guided tumor photodynamic therapy. Theranostics. 2014 Jan 15;4 (3) :229-39.|[2]Shams M, et al. Development of photodynamic therapy regimens that control primary tumor growth and inhibit secondary disease. Cancer Immunol Immunother. 2015 Mar;64 (3) :287-97.