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Nauclefine

Nauclefine (Parvine) is a natural indole alkaloid that triggers apoptosis in various cancer cells through a PDE3A-SLFN12-dependent mechanism, despite binding to PDE3A without inhibiting its enzymatic activity. It serves as a valuable research tool for studying this novel cell death pathway in both in vitro and in vivo oncology models.

Product Specifications

CAS Number

57103-51-2

Product Name Alternative

Parvine, PDE3A, Nauclefine

Field of Research

Cell Biology, Metabolism Research

Purity

99.92% (May vary between batches)

Solubility

DMSO:20 mg/mL (69.61 mM)

Smiles

O=C1N2C (C3=C (C=4C (N3) =CC=CC4) CC2) =CC=5C1=CN=CC5

Molecular Formula

C18H13N3O

Molecular Weight

287.32

Storage Conditions

Store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Notes

For research use only.

Available Sizes

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