Nauclefine
Nauclefine (Parvine) is a natural indole alkaloid that triggers apoptosis in various cancer cells through a PDE3A-SLFN12-dependent mechanism, despite binding to PDE3A without inhibiting its enzymatic activity. It serves as a valuable research tool for studying this novel cell death pathway in both in vitro and in vivo oncology models.
Product Specifications
CAS Number
57103-51-2
Product Name Alternative
Parvine, PDE3A, Nauclefine
Field of Research
Cell Biology, Metabolism Research
Purity
99.92% (May vary between batches)
Solubility
DMSO:20 mg/mL (69.61 mM)
Smiles
O=C1N2C (C3=C (C=4C (N3) =CC=CC4) CC2) =CC=5C1=CN=CC5
Molecular Formula
C18H13N3O
Molecular Weight
287.32
Storage Conditions
Store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
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