Nesbuvir
Nesbuvir is a potent and selective inhibitor of the HCV NS5B RNA-dependent RNA polymerase. It demonstrates high antiviral activity in vitro, with an IC50 of 9 nM against HCV genotype 1b replicons in hepatocellular carcinoma cells, supporting its use in hepatitis C virology and antiviral discovery research.
Product Specifications
CAS Number
691852-58-1
Product Name Alternative
Nesbuvir, NS5B polymerase, HCV 796, HCV NS5B polymerase, HCV Protease, HCVProtease, HCV796, HCV-796
Field of Research
Infectious Disease & Virology, Protein Biochemistry
Purity
98.72% (May vary between batches)
Solubility
DMSO:45 mg/mL (100.79 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.48 mM)
Smiles
CNC (=O) c1c (oc2cc (N (CCO) S (C) (=O) =O) c (cc12) C1CC1) -c1ccc (F) cc1
Molecular Formula
C22H23FN2O5S
Molecular Weight
446.49
Storage Conditions
Keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
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