L-655708
L-655708 is a highly potent and selective inverse agonist of the GABAA receptor, exhibiting a Ki of 0.45 nM. It is a valuable research tool for investigating GABAergic neurotransmission in neuropharmacology and has been utilized in both in vitro binding assays and in vivo studies exploring anxiety and sedation.
Product Specifications
CAS Number
130477-52-0
Product Name Alternative
L 655708, GABAA, GABA Receptor, GABAReceptor, L655708, L-655708
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
98.41% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.93 mM) ; DMSO:5 mg/mL (14.65 mM) ; H2O:Insoluble
Smiles
[H][C@@]12CCCN1C (=O) c1cc (OC) ccc1-n1cnc (C (=O) OCC) c21
Molecular Formula
C18H19N3O4
Molecular Weight
341.36
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
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