Lanabecestat
Lanabecestat (AZD3293) is a potent, brain-penetrant, and orally bioavailable BACE1 inhibitor (Ki: 0.4 nM) . It has been utilized in both in vitro and in vivo research models for investigating Alzheimer's disease pathology and other neurological disorders associated with amyloid-beta production.
Product Specifications
CAS Number
1383982-64-6
Product Name Alternative
AZD3293, AZD-3293, AZD 3293, BACE1, Lanabecestat, LY 3314814, LY3314814, LY-3314814
Field of Research
Neuroscience
Purity
98.55% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (8 mM) ; DMSO:80 mg/mL (193.93 mM)
Smiles
COC1CCC2 (Cc3ccc (cc3[C@@]22N=C (C) C (N) =N2) -c2cncc (c2) C#CC) CC1
Molecular Formula
C26H28N4O
Molecular Weight
412.53
Storage Conditions
Store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
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