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Fenebrutinib HCl

Fenebrutinib (GDC-0853) is an orally bioavailable, potent, and selective small molecule inhibitor of Bruton's tyrosine kinase (BTK) . It blocks BCR signaling, inhibiting the proliferation and survival of malignant B-cells in hematological cancers, as demonstrated in both in vitro and in vivo preclinical studies.

Product Specifications

CAS Number

2128304-54-9

Smiles

Cl.C[C@H]1CN (CCN1c1ccc (Nc2cc (cn (C) c2=O) -c2ccnc (N3CCn4c5CC (C) (C) Cc5cc4C3=O) c2CO) nc1) C1COC1

Molecular Formula

C37H45ClN8O4

Molecular Weight

701.27

Storage Conditions

-20°C

Notes

For research use only.

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