Firategrast
Firategrast (SB 683699) is an orally bioavailable, selective antagonist of α4β1/α4β7 integrins. It is used in research on relapsing-remitting multiple sclerosis (MS) to investigate mechanisms of lymphocyte migration into the CNS, supported by in vivo studies showing reduced CNS infiltration and modest decreases in lymphocyte subsets.
Product Specifications
CAS Number
402567-16-2
Product Name Alternative
Firategrast, SB 683699, SB683699, SB-683699, α4β1 integrin, α4β7 integrin
Field of Research
Signal Transduction
Purity
99.16% (May vary between batches)
Solubility
DMSO:90 mg/mL (180.18 mM) ; Ethanol:45 mg/mL (90.09 mM)
Smiles
CCOCc1cc (OC) c (c (OC) c1) -c1ccc (C[C@H] (NC (=O) c2c (F) cccc2F) C (O) =O) cc1
Molecular Formula
C27H27F2NO6
Molecular Weight
499.5
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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