What is the catalog number for MS9715?

The catalog number for MS9715 is orb1568338.

What sizes are available for MS9715?

MS9715 is available in the following size(s): 100 mg.

MS9715 is currently made to order / not held in immediate stock. Contact us for lead time.

MS9715

MS9715 (MS-9715) is a NSD3-targeting PROTAC designed by linking BI-9321, a NSD3 antagonist, which binds NSD3's PWWP1 domain, with an E3 ligase VHL ligand.MS9715 achieves effective and specific targeting of NSD3 and associated cMyc node in tumor cells.MS9715 effectively suppresses growth of NSD3-dependent hematological cancer cells.MS 9715 effectively suppresses NSD3-and cMyc-associated gene expression programs, resembling effects of the CRISPR-Cas9-mediated knockout of NSD3.

Product Specifications

Purity

>98%

Smiles

O=C ([C@H]1N (C ([C@@H] (NC (CCCCCCCCNC (CCCNCC2=CC (C) =C (C3=C (C4=CC=NC5=CC (F) =CC=C45) N (C) C=N3) C (C) =C2) =O) =O) C (C) (C) C) =O) C[C@H] (O) C1) N[C@H] (C6=CC=C (C7=C (C) N=CS7) C=C6) C