JP-153
JP-153 (JP153) is a novel small molecule targets the Src-FAK-Paxillin signaling, inhibits Src-dependent phosphorylation of paxillin (Y118) and downstream activation of Akt (S473) in RECs; potently inhibits VEGF-induced proliferation and migration, inhibits retinal neovascularization in the murine oxygen-induced retinopathy model.
Product Specifications
CAS Number
1802937-26-3
Purity
>98%
Smiles
O1C (C2=CC (OC) =C (OC) C (OC) =C2) C2=CC=C3C (=C2NC1=O) C=CC=C3
Molecular Formula
C21H19NO5
Molecular Weight
365.385
Notes
For research use only.
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