DBCO-PEG4-Ahx-DM1

DBCO-PEG4-Ahx-DM1 is a drug-linker conjugate composed of a potent microtubulin inhibitor DM1 and a linker DBCO-PEG4-Ahx to make antibody drug conjugate (ADC) . Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery.

Product Specifications

CAS Number

2479378-44-2

Purity

>95%

Smiles

COC1=CC (C/C (C) =C/C=C/[C@@H] (OC) [C@]2 (O) NC (OC ([C@@H] (C) C (O3) [C@]3 (C) [C@@H] (OC ([C@H] (C) N (C) C (CCCCCNC (CCOCCOCCOCCOCCNC (CCC (N4CC (C=CC=C5) =C5C#CC6=C4C=CC=C6) =O) =O) =O) =O) =O) CC7=O) C2) =O) =CC (N7C) =C1Cl