DBCO-PEG4-Ahx-DM1
DBCO-PEG4-Ahx-DM1 is a drug-linker conjugate composed of a potent microtubulin inhibitor DM1 and a linker DBCO-PEG4-Ahx to make antibody drug conjugate (ADC) . Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery.
Product Specifications
CAS Number
2479378-44-2
Purity
>95%
Smiles
COC1=CC (C/C (C) =C/C=C/[C@@H] (OC) [C@]2 (O) NC (OC ([C@@H] (C) C (O3) [C@]3 (C) [C@@H] (OC ([C@H] (C) N (C) C (CCCCCNC (CCOCCOCCOCCOCCNC (CCC (N4CC (C=CC=C5) =C5C#CC6=C4C=CC=C6) =O) =O) =O) =O) =O) CC7=O) C2) =O) =CC (N7C) =C1Cl
Molecular Formula
C68H89ClN6O17
Molecular Weight
1297.92
Notes
For research use only.
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