What is the catalog number for Fosaprepitant dimeglumine?

The catalog number for Fosaprepitant dimeglumine is orb1307445.

What sizes are available for Fosaprepitant dimeglumine?

Fosaprepitant dimeglumine is available in the following size(s): 5 mg, 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does Fosaprepitant dimeglumine come in?

Fosaprepitant dimeglumine is available in 5 different pack sizes.

Is Fosaprepitant dimeglumine in stock?

Fosaprepitant dimeglumine is currently made to order / not held in immediate stock. Contact us for lead time.

Fosaprepitant dimeglumine

Fosaprepitant dimeglumine is a water-soluble prodrug of aprepitant. Upon intravenous administration, it is rapidly converted to aprepitant, which acts as a selective neurokinin-1 (NK1) receptor antagonist to prevent substance P-mediated emesis. It is widely used in antiemetic research, including in vivo models of chemotherapy-induced nausea and vomiting (CINV) and in vitro receptor binding studies.

Product Specifications

CAS Number

265121-04-8

Product Name Alternative

Tachykinin receptor, substance-P, vomiting, Fosaprepitant dimeglumine, Fosaprepitant dimeglumine salt, L785298, L-785298, MK 0517, MK0517, MK-0517, nociception, NK1, NK receptor, neuropeptide, Neurokinin Receptor, Neurokinin receptor, Neurokininreceptor, L 785298, antagonist, Aprepitant, chemotherapy-induced

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

97.39% (May vary between batches)

Solubility

H2O:124 mg/mL (123.4 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:185 mg/mL (184.11 mM)

Smiles

CNC[C@H] (O) [C@@H] (O) [C@H] (O) [C@H] (O) CO.CNC[C@H] (O) [C@@H] (O) [C@H] (O) [C@H] (O) CO.C[C@@H] (O[C@H]1OCCN (Cc2nn (c (=O) [nH]2) P (O) (O) =O) [C@H]1c1ccc (F) cc1) c1cc (cc (c1) C (F) (F) F) C (F) (F) F