Thalidomide-O-amido-PEG2-C2-NH2 TFA
This compound is a thalidomide-based cereblon E3 ligase ligand conjugated to a short PEG linker, designed for constructing PROTAC molecules. It is widely used in chemical biology and drug discovery research for targeted protein degradation studies in both cellular and preclinical models.
Product Specifications
CAS Number
1957235-75-4
Product Name Alternative
Inhibit, Inhibitor, E3LigaseLigandLinkerConjugate, E3 Ligase Ligand-Linker Conjugates 24, E3 Ligase Ligand-Linker Conjugates 24 TFA, E3 Ligase Ligand-Linker Conjugates, E3 Ligase Ligand-Linker Conjugate, E3 Ligase LigandLinker Conjugate, Cereblon, Cereblon Ligand-Linker Conjugates 10, Cereblon Ligand-Linker Conjugates 10 TFA, Thalidomide O amido PEG2 C2 NH2 TFA, ThalidomideOamidoPEG2C2NH2 TFA, Thalidomide-O-amido-PEG-2-C2-NH2 TFA, Thalidomide-O-amido-PEG2-C2-NH2 TFA
Field of Research
Cell Biology, Immunology & Inflammation; Metabolism Research; Pharmacology & Drug Discovery, Pharmacology & Drug Discovery
Purity
95.74% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.47 mM) ; H2O:150 mg/mL (260.2 mM)
Smiles
O=C (NCCOCCOCCN) COC1=CC=CC (C (N2C (CC3) C (NC3=O) =O) =O) =C1C2=O.O=C (O) C (F) (F) F
Molecular Formula
C23H27F3N4O10
Molecular Weight
576.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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