(S, R, S) -AHPC-PEG2-NH2 hydrochloride
This compound is an E3 ligase ligand-linker conjugate, featuring the (S, R, S) -AHPC VHL ligand connected via a two-unit polyethylene glycol (PEG2) linker and an amine terminus. It serves as a key intermediate for constructing PROTAC molecules, which are used in both in vitro and in vivo studies to investigate targeted protein degradation.
Product Specifications
CAS Number
2097973-72-1
Product Name Alternative
AHPC-PEG2-NH2 Hydrochloride, (S, R, S) AHPC PEG2 NH2 hydrochloride, (S, R, S) AHPCPEG2NH2 hydrochloride, (S, R, S) -AHPC-PEG-2-NH2 hydrochloride, E3 Ligase Ligand-Linker Conjugates, E3 Ligase LigandLinker Conjugate, E3 Ligase Ligand-Linker Conjugate, E3 ligase Ligand-Linker Conjugates 6, E3LigaseLigandLinkerConjugate, inhibit, Inhibitor, VHL, VH032-PEG2-NH2 hydrochloride, VH032-PEG2-NH2 Hydrochloride, VHL Ligand-Linker Conjugates 3, VHL Ligand-Linker Conjugates 3 hydrochloride, VHL Ligand-Linker Conjugates 3 Hydrochloride
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
97.81% (May vary between batches)
Solubility
H2O:100 mg/mL (163.35 mM) ; DMSO:100 mg/mL (163.35 mM)
Smiles
O=C ([C@H]1N (C ([C@@H] (NC (COCCOCCN) =O) C (C) (C) C) =O) C[C@H] (O) C1) NCC2=CC=C (C3=C (C) N=CS3) C=C2.Cl
Molecular Formula
C28H42ClN5O6S
Molecular Weight
612.18
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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