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Cabozantinib S-malate

Cabozantinib S-malate (XL184) is the malate salt of the small molecule kinase inhibitor cabozantinib. This orally available compound is used in cancer research, where it has demonstrated activity in both in vitro assays and in vivo models targeting various receptor tyrosine kinases.

Product Specifications

CAS Number

1140909-48-3

Product Name Alternative

XL-184, XL184, XL 184, TAMReceptor, TAM Receptor, VEGFR, VEGFR3/FLT4, VEGFR2/KDR, cMet, cMet/HGFR, c-Met, cKit, Apoptosis, AXL, Cabozantinib, Cabozantinib Malate, Cabozantinib S malate, Cabozantinib Smalate, Cabozantinib S-malate, BMS 907351, BMS907351, BMS-907351, Kit, HGFR

Field of Research

Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Purity

98.00% (May vary between batches)

Solubility

Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:16.67 mg/mL (26.23 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)

Smiles

O[C@@H] (CC (O) =O) C (O) =O.COc1cc2nccc (Oc3ccc (NC (=O) C4 (CC4) C (=O) Nc4ccc (F) cc4) cc3) c2cc1OC

Molecular Formula

C32H30FN3O10

Molecular Weight

635.59

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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