RITA
RITA (NSC-652287) is a small molecule that disrupts the p53-MDM2 interaction, similar to nutlin-3. It induces DNA-DNA and DNA-protein crosslinks without causing detectable single-strand breaks. This compound is used in cancer research to study p53 reactivation and its effects in both cellular and animal models.
Product Specifications
CAS Number
213261-59-7
Product Name Alternative
NSC 652287
Field of Research
Cell Biology
Purity
97.76% (May vary between batches)
Bioactivity
P53-MDM2 interaction inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 20 mg/ml)
Smiles
OCc1ccc (s1) -c1ccc (o1) -c1ccc (CO) s1
Molecular Formula
C14H12O3S2
Molecular Weight
292.4
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
5,5'- (2,5-Furandiyl) bis-2-thiophenemethanol
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