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RITA

RITA (NSC-652287) is a small molecule that disrupts the p53-MDM2 interaction, similar to nutlin-3. It induces DNA-DNA and DNA-protein crosslinks without causing detectable single-strand breaks. This compound is used in cancer research to study p53 reactivation and its effects in both cellular and animal models.

Product Specifications

CAS Number

213261-59-7

Product Name Alternative

NSC 652287

Field of Research

Cell Biology

Purity

97.76% (May vary between batches)

Bioactivity

P53-MDM2 interaction inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to 20 mg/ml)

Smiles

OCc1ccc (s1) -c1ccc (o1) -c1ccc (CO) s1

Molecular Formula

C14H12O3S2

Molecular Weight

292.4

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

5,5'- (2,5-Furandiyl) bis-2-thiophenemethanol

Available Sizes

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