Caspofungin Acetate

Caspofungin Acetate (MK-0991) is a semisynthetic echinocandin antifungal agent derived from Glarea lozoyensis. It is used in research to study its potent in vitro and in vivo activity against Aspergillus and Candida species, primarily by inhibiting beta- (1,3) -D-glucan synthesis in fungal cell walls.

Product Specifications

CAS Number

179463-17-3

Product Name Alternative

Caspofungin Acetate, Caspofungin diacetate, Cancidas, Antibiotic, antifungal, 1,3-beta-D-glucan synthesis, L743872, L-743872, L-743872 diacetate, L743873, L-743873, Fungal, fungal cell wall, Inhibitor, L 743872, L 743873, inhibit, MK0991, MK-0991, MK-0991 diacetate, MK 0991

Field of Research

Infectious Disease & Virology, Pharmacology & Drug Discovery

Purity

97.22% (May vary between batches)

Solubility

DMSO:102 mg/mL (84.06 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (2.72 mM) ; H2O:100 mg/mL (82.41 mM)

Smiles

CC (O) =O.CC (O) =O.CCC (C) CC (C) CCCCCCCCC (=O) N[C@H]1C[C@@H] (O) [C@@H] (NCCN) NC (=O) [C@@H]2[C@@H] (O) CCN2C (=O) [C@@H] (NC (=O) [C@@H] (NC (=O) [C@@H]2C[C@@H] (O) CN2C (=O) [C@@H] (NC1=O) [C@@H] (C) O) [C@@H] (O) [C@H] (O) c1ccc (O) cc1) [C@H] (O) CCN