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Ataluren

Ataluren (PTC124) is an orally bioavailable small molecule designed to promote readthrough of nonsense mutations. It is conditionally approved in Europe for ambulatory Duchenne Muscular Dystrophy and is widely used in preclinical in vitro and in vivo studies investigating nonsense mutation suppression across various genetic disorders.

Product Specifications

CAS Number

775304-57-9

Product Name Alternative

Inhibit, Inhibitor, Autophagy, Ataluren, CFTR, Cystic fibrosis transmembrane conductance regulator, PTC 124, PTC124, PTC-124

Field of Research

Cell Biology, Pharmacology & Drug Discovery

Purity

99.16% (May vary between batches)

Solubility

H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+90% Corn Oil:2.5 mg/mL (8.8 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:69 mg/mL (242.75 mM)

Smiles

FC1=C (C2=NC (=NO2) C3=CC (C (O) =O) =CC=C3) C=CC=C1

Molecular Formula

C15H9FN2O3

Molecular Weight

284.24

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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