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Tenovin-6

Tenovin-6 is a small molecule activator of the p53 tumor suppressor protein, enhancing its transcriptional activity. It is utilized in cancer research to study p53-dependent pathways, demonstrating effects in both cellular assays and in vivo models of tumorigenesis.

Product Specifications

CAS Number

1011557-82-6

Product Name Alternative

Sirtuin, SIRT3, SIRT2, SIRT1, protein-deacetylating, Tenovin 6, Tenovin6, Tenovin-6, inhibit, Inhibitor, MDM2, MDM-2/p53, Dihydroorotate Dehydrogenase, DHODH, degradation, acetylation, Autophagy

Field of Research

Cell Biology, Epigenetics & Chromatin, Metabolism Research, Molecular Biology

Purity

97.71% (May vary between batches)

Solubility

Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:90 mg/mL (197.96 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.26 mM) ; DMSO:91 mg/mL (200.16 mM)

Smiles

CN (C) CCCCC (=O) Nc1ccc (NC (=S) NC (=O) c2ccc (cc2) C (C) (C) C) cc1

Molecular Formula

C25H34N4O2S

Molecular Weight

454.63

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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