Reversine
Reversine is a synthetic 2,6-disubstituted purine analog that potently inhibits Aurora kinase isoforms A, B, and C with IC50 values ranging from 150 to 500 nM. This cell-permeable compound is widely used in vitro to study cell cycle regulation, cytokinesis, and cellular dedifferentiation, and has been applied in vivo within experimental models of tissue regeneration.
Product Specifications
CAS Number
656820-32-5
Product Name Alternative
Reversine, inhibit, Inhibitor, Autophagy, AuroraKinase, Aurora B, Aurora A, Aurora Kinase, Aurora C, Adenosine Receptor, AdenosineReceptor, A3
Field of Research
Stem Cell & Developmental Biology
Purity
>98%
Bioactivity
Reverses cells to multipotent stem cells; Mps1 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 7 mg/ml) .
Smiles
C1CCC (CC1) Nc1nc (Nc2ccc (cc2) N2CCOCC2) nc2[nH]cnc12
Molecular Formula
C21H27N7O
Molecular Weight
383.50
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
2- (4-Morpholinoanilino) -6-cyclohexylaminopurine
Available Sizes
Frequently Asked Questions
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