PI3K-IN-1
PI3K-IN-1 (Voxtalisib Analogue) is a potent small molecule inhibitor primarily targeting the p110γ isoform of PI3K and mTOR, with additional activity against DNA-PK. This dual inhibitor is utilized in biochemical and cellular research to investigate oncogenic signaling pathways, including in cancer models both in vitro and in vivo.
Product Specifications
CAS Number
1349796-36-6
Product Name Alternative
PI3Kγ, PI3Kβ, PI3Kδ, PI3Kα, PI3K, PI3K IN 1, PI3KIN1, PI-3K-IN-1, PI3K-IN-1, XL 765, XL-147 derivative 1, XL765, XL-765, thyroid, SAR245409, SAR-245409, SAR 245409, Voxtalisib Analogue, DNA-PK, DNAPK, fibrosis, extraocular, ophthalmopathy
Field of Research
Molecular Biology, Signal Transduction
Purity
97.03% (May vary between batches)
Solubility
DMSO:1 mg/mL (1.67 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.67 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
COc1cc (Nc2nc3ccccc3nc2NS (=O) (=O) c2ccc (NC (=O) c3ccc (OC) c (C) c3) cc2) cc (OC) c1
Molecular Formula
C31H29N5O6S
Molecular Weight
599.66
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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