Buparlisib
Buparlisib (BKM120) is a potent and orally bioavailable pan-class I PI3K inhibitor, targeting p110α, β, and δ isoforms. It is widely used in preclinical cancer research, demonstrating activity in both in vitro cell-based assays and in vivo tumor models for studying PI3K pathway dysregulation.
Product Specifications
CAS Number
944396-07-0
Product Name Alternative
NVP-BKM120; BKM-120
Field of Research
Cell Biology
Purity
>98%
Bioactivity
PI3K inhibitor (pan-Class I)
Form
Powder
Solubility
Soluble in DMSO (up to 15 mg/ml)
Smiles
Nc1cc (c (cn1) -c1cc (nc (n1) N1CCOCC1) N1CCOCC1) C (F) (F) F
Molecular Formula
C18H21F3N6O2
Molecular Weight
410.4
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
5- (2,6-Dimorpholin-4-ylpyrimidin-4-yl) -4- (trifluoromethyl) pyridine-2-amine
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