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Buparlisib

Buparlisib (BKM120) is a potent and orally bioavailable pan-class I PI3K inhibitor, targeting p110α, β, and δ isoforms. It is widely used in preclinical cancer research, demonstrating activity in both in vitro cell-based assays and in vivo tumor models for studying PI3K pathway dysregulation.

Product Specifications

CAS Number

944396-07-0

Product Name Alternative

NVP-BKM120; BKM-120

Field of Research

Cell Biology

Purity

>98%

Bioactivity

PI3K inhibitor (pan-Class I)

Form

Powder

Solubility

Soluble in DMSO (up to 15 mg/ml)

Smiles

Nc1cc (c (cn1) -c1cc (nc (n1) N1CCOCC1) N1CCOCC1) C (F) (F) F

Molecular Formula

C18H21F3N6O2

Molecular Weight

410.4

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

5- (2,6-Dimorpholin-4-ylpyrimidin-4-yl) -4- (trifluoromethyl) pyridine-2-amine

Available Sizes

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