Ruxolitinib
Ruxolitinib is a potent and selective JAK1/2 inhibitor (IC50=3.3/2.8 nM) . It demonstrates antitumor effects by inducing autophagy and apoptosis, making it a valuable tool for in vitro and in vivo research in oncology and immunology.
Product Specifications
CAS Number
941678-49-5
Product Name Alternative
INCB 018424
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Purity
>98%
Bioactivity
JAK inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 28 mg/ml) or in Ethanol (up to 15 mg/ml with warming) .
Smiles
N#CC[C@H] (C1CCCC1) n1cc (cn1) -c1ncnc2[nH]ccc12
Molecular Formula
C17H18N6
Molecular Weight
306.37
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
βR-Cyclopentyl-4- (7H-pyrrolo[2,3-d]pyrimidin-4-yl) -1H-pyrazole-1-propanenitrile
Available Sizes
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