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MC-Val-Ala-PAB-PNP

MC-Val-Ala-PAB-PNP is a protease-cleavable linker used in the synthesis of antibody-drug conjugates (ADCs) . This chemical tool enables the targeted delivery of cytotoxic payloads in both in vitro and in vivo cancer research, facilitating the study of novel therapeutic strategies.

Product Specifications

CAS Number

1639939-40-4

Product Name Alternative

Cleavable, ADC Linker, ADCLinker, ADC Linkers, Antibody-drug conjugates linkers, inhibit, Inhibitor, MCValAlaPABPNP, MC-Val-Ala-PAB-PNP, MC Val Ala PAB PNP

Field of Research

Pharmacology & Drug Discovery

Purity

96.04% (May vary between batches)

Solubility

DMSO:50 mg/mL (76.73 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.07 mM)

Smiles

O (C (OCC1=CC=C (NC ([C@@H] (NC ([C@@H] (NC (CCCCCN2C (=O) C=CC2=O) =O) [C@H] (C) C) =O) C) =O) C=C1) =O) C3=CC=C (N (=O) =O) C=C3

Molecular Formula

C32H37N5O10

Molecular Weight

651.66

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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