CX-6258
CX-6258 is a potent and selective oral inhibitor of Pim kinases (Pim-1, -2, -3) with IC50 values of 5 nM, 25 nM, and 16 nM, respectively. It is used in preclinical research to investigate Pim kinase function in cancer cell proliferation and survival, both in vitro and in vivo.
Product Specifications
CAS Number
1202916-90-2
Product Name Alternative
Inhibit, Inhibitor, Bad, 4E-BP1, CX 6258, CX6258, CX-6258, Pim2, Pim, Pim1, Pim kinases, Pim3
Field of Research
Epigenetics & Chromatin, Signal Transduction
Purity
95.88% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.33 mM) ; DMSO:22.5 mg/mL (48.71 mM)
Smiles
CN1CCCN (CC1) C (=O) c1cccc (c1) -c1ccc (\C=C2\C (=O) Nc3ccc (Cl) cc23) o1
Molecular Formula
C26H24ClN3O3
Molecular Weight
461.94
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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