Ibrutinib
Ibrutinib is a potent, selective, and irreversible inhibitor of Bruton's tyrosine kinase (BTK) with an IC50 of 0.5 nM. It suppresses B-cell proliferation and survival, demonstrating antitumor efficacy in both in vitro assays and in vivo models of B-cell malignancies like chronic lymphocytic leukemia.
Product Specifications
CAS Number
936563-96-1
Product Name Alternative
PCI-32765
Field of Research
Immunology & Inflammation
Purity
>98%
Bioactivity
BTK inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to at least 25 mg/ml)
Smiles
NC1=C2C (N (N=C2C3=CC=C (OC4=CC=CC=C4) C=C3) [C@H]5CN (C (C=C) =O) CCC5) =NC=N1
Molecular Formula
C25H24N6O2
Molecular Weight
440.51
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
1-[ (3R) -3-[4-amino-3- (4-phenoxyphenyl) pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one
Available Sizes
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