UNC-0379
UNC0379 is a potent and selective inhibitor that targets the SETD8 methyltransferase through a substrate-competitive mechanism. This tool compound is widely used in biochemical and cellular research to probe the biological functions of histone H4 lysine 20 methylation in processes such as DNA damage repair and cell cycle regulation.
Product Specifications
CAS Number
1620401-82-2
Product Name Alternative
OVCAR3, Ovarian cancer, neuroblastoma, lysine methyltransferase, JHOS3, inhibit, Inhibitor, HGSOC, HistoneMethyltransferase, Histone Methyltransferase, antitumor, SETD8, pulmonary fibrosis, UNC0379, UNC-0379, UNC 0379
Field of Research
Epigenetics & Chromatin, Neuroscience
Purity
>98%
Bioactivity
SETD8 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 30 mg/ml) .
Smiles
COc1cc2nc (nc (NCCCCCN3CCCC3) c2cc1OC) N1CCCC1
Molecular Formula
C23H35N5O2
Molecular Weight
413.56
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
6,7-Dimethoxy-2- (pyrrolidin-1-yl) -N- (5- (pyrrolidin-1-yl) -pentyl) quinazolin-4-amine
Available Sizes
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