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XMD17-109

XMD17-109 (ERK5-IN-1) is a selective inhibitor of ERK5 with an EC50 of 4.2 μM in HEK293 cells. This compound is a valuable research tool for investigating the role of ERK5 signaling in cancer and inflammation, supporting both in vitro cellular studies and in vivo preclinical research.

Product Specifications

CAS Number

1435488-37-1

Product Name Alternative

Extracellular signal regulated kinases, ERK, ERK5-IN-1, ERK5, Inhibitor, inhibit, XMD17 109, XMD17109, XMD-17-109, XMD17-109

Field of Research

Signal Transduction

Purity

98.75% (May vary between batches)

Solubility

H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.17 mM) ; DMSO:93 mg/mL (145.59 mM) ; Ethanol:93 mg/mL (145.59 mM)

Smiles

CCOc1cc (ccc1Nc1ncc2N (C) C (=O) c3ccccc3N (C3CCCC3) c2n1) C (=O) N1CCC (CC1) N1CCN (C) CC1

Molecular Formula

C36H46N8O3

Molecular Weight

638.8

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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