(E) -KPT330
(E) -KPT330 is a selective CRM1 inhibitor that blocks nuclear protein export. This activity induces cell cycle arrest and apoptosis in mesothelioma cells in vitro and has shown antitumor efficacy in vivo xenograft models, supporting its investigation in cancer research.
Product Specifications
CAS Number
1421923-86-5
Product Name Alternative
CRM1, (E) -KPT 330, (E) -KPT330, (E) -KPT-330, (E) -RN, KPT330, , KPT330, (E), KPT-330, (E) -, RN, XPO1
Field of Research
Pharmacology & Drug Discovery
Purity
98.69% (May vary between batches)
Solubility
DMSO:4.44 mg/mL (10.02 mM)
Smiles
FC (F) (F) c1cc (cc (c1) C (F) (F) F) -c1ncn (\C=C\C (=O) NNc2cnccn2) n1
Molecular Formula
C17H11F6N7O
Molecular Weight
443.31
Storage Conditions
-20°C
Notes
For research use only.
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