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(E) -KPT330

(E) -KPT330 is a selective CRM1 inhibitor that blocks nuclear protein export. This activity induces cell cycle arrest and apoptosis in mesothelioma cells in vitro and has shown antitumor efficacy in vivo xenograft models, supporting its investigation in cancer research.

Product Specifications

CAS Number

1421923-86-5

Product Name Alternative

CRM1, (E) -KPT 330, (E) -KPT330, (E) -KPT-330, (E) -RN, KPT330, , KPT330, (E), KPT-330, (E) -, RN, XPO1

Field of Research

Pharmacology & Drug Discovery

Purity

98.69% (May vary between batches)

Solubility

DMSO:4.44 mg/mL (10.02 mM)

Smiles

FC (F) (F) c1cc (cc (c1) C (F) (F) F) -c1ncn (\C=C\C (=O) NNc2cnccn2) n1

Molecular Formula

C17H11F6N7O

Molecular Weight

443.31

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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