B-Raf IN 1
B-Raf IN 1 is a potent dual inhibitor of B-Raf and c-Raf kinases, with IC50 values of 24 nM and 25 nM, respectively. This compound is a valuable research tool for studying MAPK/ERK signaling in cancer biology and for conducting in vitro cellular assays targeting Raf-dependent proliferation.
Product Specifications
CAS Number
950736-05-7
Product Name Alternative
Inhibit, Inhibitor, B Raf IN 1, BRaf IN 1, B-Raf IN 1, B-Raf, C-Raf, Raf kinases, Raf
Field of Research
Signal Transduction
Purity
97.22% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (4.85 mM) ; DMSO:50 mg/mL (96.99 mM)
Smiles
CN (C) Cc1ccc (cc1) -c1cnn2c (ccnc12) -c1cccc (NC (=O) c2cccc (c2) C (F) (F) F) c1
Molecular Formula
C29H24F3N5O
Molecular Weight
515.53
Storage Conditions
-20°C
Notes
For research use only.
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