Phe-Lys (Trt) -PAB
Phe-Lys (Trt) -PAB is a cathepsin-cleavable linker used in ADC research. It enables targeted drug release in lysosomes, a mechanism validated in both in vitro cytotoxicity assays and in vivo xenograft models for cancer therapy development.
Product Specifications
CAS Number
1116085-99-4
Product Name Alternative
ADC Linkers, ADC Linker, ADCLinker, Antibody-drug conjugates linkers, Cleavable, inhibit, Inhibitor, Phe-Lys (Trt) -PAB, PheLys (Trt) PAB, Phe Lys (Trt) PAB
Field of Research
Pharmacology & Drug Discovery
Purity
97.87% (May vary between batches)
Smiles
OCC (C=C1) =CC=C1NC ([C@@H] (NC ([C@@H] (N) CC2=CC=CC=C2) =O) CCCCNC (C3=CC=CC=C3) (C4=CC=CC=C4) C5=CC=CC=C5) =O
Molecular Formula
C41H44N4O3
Molecular Weight
640.81
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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