TMP269
TMP269 is a potent and selective class IIa HDAC inhibitor, demonstrating IC50 values of 157 nM, 97 nM, 43 nM, and 23 nM for HDAC4, HDAC5, HDAC7, and HDAC9, respectively. This small molecule is a valuable research tool for investigating epigenetic mechanisms in cancer, neurodegenerative diseases, and metabolic disorders in both cellular and animal models.
Product Specifications
CAS Number
1314890-29-3
Product Name Alternative
HDAC, HDAC7, HDAC9, HDAC5, HDAC4, Histone deacetylases, Inhibitor, inhibit, TMP-269, TMP269, TMP 269
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.41 mM) ; Ethanol:2 mg/mL (3.89 mM) ; DMSO:225 mg/mL (437.3 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
FC (F) (F) c1nc (no1) -c1cccc (c1) C (=O) NCC1 (CCOCC1) c1nc (cs1) -c1ccccc1
Molecular Formula
C25H21F3N4O3S
Molecular Weight
514.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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