XAV-939
XAV-939 is a potent and selective inhibitor of Tankyrase 1 and 2 (TNKS1/2), thereby blocking Wnt/β-catenin signaling. This small molecule is widely used in biochemical and cellular assays to investigate Wnt pathway roles in cancer, stem cell biology, and regeneration, with utility in both in vitro and in vivo research models.
Product Specifications
CAS Number
284028-89-3
Product Name Alternative
Bcatenin, Beta catenin, beta-catenin, betacatenin, PARP, poly ADP ribose polymerase, NVP-XAV 939, NVP-XAV939, NVP-XAV-939, inhibit, Inhibitor, TNKS1, TNKS2, XAV 939, XAV939, XAV-939, Wnt/β-catenin, Wnt, Wnt/b-catenin, Wnt/betacatenin, β-catenin, βcatenin
Field of Research
Stem Cell & Developmental Biology
Purity
>98%
Bioactivity
Tankyrase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml) .
Smiles
FC (F) (F) C1=CC=C (C=C1) C1=NC (=O) C2=C (CCSC2) N1
Molecular Formula
C14H11F3N2OS
Molecular Weight
312.3
Storage Conditions
RT
Notes
For research use only.
Other Product Names
2-[4- (Trifluoromethyl) phenyl]-7,8-dihydro-5H-thiino[4,3-d]pyrimidin-4-ol
Available Sizes
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