3-Methyladenine
3-Methyladenine (3-MA) is an autophagy inhibitor functioning through the inhibition of class III PI3K VPS34 (IC50=25 μM) and class IB PI3Kγ (IC50=60 μM) . It is widely used as a pharmacological tool in both in vitro and in vivo studies to investigate autophagic pathways in cancer, neurodegeneration, and other cellular processes.
Product Specifications
CAS Number
5142-23-4
Product Name Alternative
3-MA
Field of Research
Cell Biology
Purity
>98%
Bioactivity
PI3K inhibitor
Form
Powder
Solubility
Soluble in Water (up to 5 mg/ml), or in DMSO (up to 3 mg/ml), or in DMF (up to 10 mg/ml) .
Smiles
Cn1cnc (N) c2ncnc12
Molecular Formula
C6H7N5
Molecular Weight
149.2
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
3-Methyl-3H-purin-6-amine
Available Sizes
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