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3-Methyladenine

3-Methyladenine (3-MA) is an autophagy inhibitor functioning through the inhibition of class III PI3K VPS34 (IC50=25 μM) and class IB PI3Kγ (IC50=60 μM) . It is widely used as a pharmacological tool in both in vitro and in vivo studies to investigate autophagic pathways in cancer, neurodegeneration, and other cellular processes.

Product Specifications

CAS Number

5142-23-4

Product Name Alternative

3-MA

Field of Research

Cell Biology

Purity

>98%

Bioactivity

PI3K inhibitor

Form

Powder

Solubility

Soluble in Water (up to 5 mg/ml), or in DMSO (up to 3 mg/ml), or in DMF (up to 10 mg/ml) .

Smiles

Cn1cnc (N) c2ncnc12

Molecular Formula

C6H7N5

Molecular Weight

149.2

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

3-Methyl-3H-purin-6-amine

Available Sizes

Frequently Asked Questions

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