P7C3

The P7C3 class of neuroprotective compounds not only prevents neuronal death but also maintains axonal integrity following injury, as demonstrated in rodent blast TBI models. This activity is associated with the activation of nicotinamide phosphoribosyltransferase (NAMPT), enhancing NAD+ salvage. These molecules are valuable tools for researching neuroprotection in models of traumatic brain injury and neurodegeneration.